Numerous studies over the past 25 years have linked higher DHEA with various health benefits, including preventing fat gain. Let’s explore this research.
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“In our study, we found out that the level of DHEA-S decreased significantly as BMI and waist circumference increased in women. In many studies, the results are found similar to our study (21–23). Hernandez-Morante et al. (24) presented that DHEA- S treatment increased adiponectin gene expression and that this mechanism was effective in preventing obesity.” (Sayin et al 2020)
00:00 DHEA is hormone. It begins to decline at about age 25.
00:07 At age 60 or 70, DHEA production has declined by about 90%.
00:13 DHEA is linked with immune health, metabolic health, memory, and cognition.
00:21 After menopause, adrenals become the sole source of androgens in the body.
00:45 Consider taking DHEA before trying hormone replacement therapy.
02:00 Active DHEA is made by your adrenals. It is in equilibrium with DHEA-S (DHEA-sulfate).
02:30 Metabolites adhere to a circadian rhythm. Be consistent about bloodwork timing.
03:45 DHEA gets converted to 4-dione, then, through aromatization, into estrogen.
06:55 Low DHEA sulfate levels are linked with higher mortality and disease.
07:25 DHEA supplementation in incorrect doses can accelerate hair loss and increase estrogen.
08:00 Dosing Men: 10 mg/ 10 years of life. Pay attention to your body’s feedback.
09:00 Dosing Women: 75% less than men. 10 mg/ 10 years of life multiplied by .25 (25%)
12:45 Micronized DHEA may be a little better absorbed. Transdermal is not necessary.
14:10 Women with PCOS should not take DHEA.
15:00 Insulin drives androgens in women. Spironolactone, a med taken for PCOS, is an antiandrogen.
15:50 Work with your doctor. Test your DHEA sulfate blood levels.
16:55 Low doses of estrogen has benefits for men in their cognition, brain function and mental health.