Gut Bacteria

The 5 Main Ways Gut Bacteria Interfere with Your Metabolism

by Mike Mutzel


Much of the initial understanding about how the gut and its associated bacteria contribute to obesity and metabolism emerged from the lab of biologist Jeffrey Gordon, MD, at the Washington University School of Medicine in St. Louis.

Gordon’s team discovered that when eight-week-old germ-free mice are inoculated with the fecal contents of ordinary mice, their fat content increased by 57 percent, even though they ate 29 percent less animal chow.

 1) Gut Bacteria Affect Fat Hormones (fasting induced adipose factor)

Gordon’s group found that adding intestinal microbes into germ-free mice was associated with increased transport of carbohydrates from the intestine to the liver. This interfered with signals from a gut hormone that inhibits a particular enzyme, in this case an enzyme that normally delivers fat from the liver to the fat cells. The end result is more fat accumulation in the liver and abdomen.

The Main Ways Gut Bacteria Interfere with Your Metabolism

Tip: Like it or not, we all have bacteria in our gut. The key is to eat a diet rich in color, fiber and protein to foster the growth of the good guys. Supplementing with whey protein, inulin, and Bifidobacteria and Saccharomyces boulardii based-probiotics may help.

2) Imbalanced Gut Bacteria Create Gut Inflammation, Insulin Resistance

The presence of harmful intestinal bacteria correlate with the degree of weight loss or gain later in life, independent of calories.

Researchers have found that babies delivered vaginally are immediately inoculated with their mother’s vaginal flora, which is dominated by healthy lactobacillus and Prevotella strains. And scientists know that infant inoculation with maternal bacteria is among the most powerful environmental variables molding our gut, and hence our metabolism.

In contrast, babies born by C-section are inoculated by the more pathogenic bacteria, common to the skin and hospital air, such as Staphylococcus aureus and Clostridium difficile. Incidentally, studies link child and adult microflora profiles rich in these bacteria to both obesity and diabetes.

A recent study of 1,255 children found that the prevalence of obesity in children born via Cesarean section by age three is twice that of children born vaginally.
Tip: Eat organic foods, rich in color and phytonutrients. Limit consumption of animal products given antibiotics and drink filtered water. Advise “parents-to-be” to birth their children naturally, breast feed and avoid antibiotics during the first year of life.

3) Low Bacterial Diversity Slows Down Your Metabolism

A recent analysis of several human studies suggests that obese people tend to have a lower level of bacterial diversity, a higher level of Staphylococcus aureus, more intestinal bacterial overgrowth, and a lower level of Bifidobacteria compared to lean people. Bifidobacteria are well known to be more “friendly” strains, while Staphylococcus aureus are known to be more immune stimulating.

Tip: A diverse diet, rich in phyto-nutrients will increase bacterial diversity. Eat as many herbs, spices and color as you can.

4) Methane Producing Bacteria Slow Down Your Gut and Increase Food Absorption

Researchers at Cedar-Sinai Medical Center in los Angeles found that obese people have greater levels of intestinal methane-producing bacteria known as Methanobrevibacter smithii. This bacteria slows down intestinal transit time by up to 60 percent, prolonging the period during which intestinal bacterial are exposed to food. As a result, more calories are absorbed from that food, and there is more weight gain. That’s one reason why even if you were to eat fewer calories than you actually burn, imbalances in your gut microflora might cause you to gain weight.

Tip: The oral probiotic bacteria, Streptococcus salivarius DSM 14685 has been shown to reduce sulfur-producing bacteria, at least in the mouth. It’s worth considering.

5) High-Fat, High-Carbohydrate Diets Can Make You Fat: the role of endotoxin

I feel that everyone should know how eating the western diet of high-calorie diets in general shift our gut ecology, increasing the absorption of endotoxin, which cranks up inflammation in the gut, liver, and fat tissues; resulting in fat gain.

The ensuing inflammation and deranged metabolism has been coined, metabolic endotoxemia.
Harvard scientists recently found that supplementing the diets of mice with an enzyme called alkaline phosphatase, the absorption of endotoxin is reduced, preventing fat gain and metabolic disorders. Thankfully we all have high levels of this enzyme found on the surface of our intestinal wall.

Tip: Bile acids help to reduce endotoxin absorption, which is why it’s so important to be mindful and chew when you eat (bile release is part of the parasympathetic response). Avoid acid-suppressing medications, artificial sweeteners, and acidic foods, such as hard cheeses and refined carbohydrates, as they reduce alkaline phosphatase’s protective ability.
If you eat a high-fat diet, make sure to pair it with some color and fiber. (This will minimize endotoxin absorption.)


Chapter 8 of Belly Fat Effect unveils the whole story about gut bacteria, the circadian clock system and metabolism, fat burning, appetite, and more.


Join the conversation

  1. I get pleasure from, result in I found exactly what I used to be looking for. You have ended my four day long hunt! God Bless you man. Have a nice day. Bye

  2. Thanks for your help Mike. Can you tell me where I can buy this Probiomax DDS and oral probiotics with L. Plantarum? spelling?

  3. Hello Web Admin, I noticed that your On-Page SEO is is missing a few factors, for one you do not use all three H tags in your post, also I notice that you are not using bold or italics properly in your SEO optimization. On-Page SEO means more now than ever since the new Google update: Panda. No longer are backlinks and simply pinging or sending out a RSS feed the key to getting Google PageRank or Alexa Rankings, You now NEED On-Page SEO. So what is good On-Page SEO?First your keyword must appear in the title.Then it must appear in the URL.You have to optimize your keyword and make sure that it has a nice keyword density of 3-5% in your article with relevant LSI (Latent Semantic Indexing). Then you should spread all H1,H2,H3 tags in your article.Your Keyword should appear in your first paragraph and in the last sentence of the page. You should have relevant usage of Bold and italics of your keyword.There should be one internal link to a page on your blog and you should have one image with an alt tag that has your keyword….wait there's even more Now what if i told you there was a simple WordPress plugin that does all the On-Page SEO, and automatically for you? That's right AUTOMATICALLY, just watch this 4minute video for more information at. <a href="">Seo Plugin</a>

  4. The gamers can buy personalized birthday invitations online at affordable prices.
    In accordance with the option of multi player games, it's not
    necessary that all future snaps are uploaded when they're created.
    Roy D'Silva candy crush saga cheats is a straightforward
    process. If you have for your personal consideration. There are various modes
    to entertain people with its high quality picture formation.

  5. Another option to have a secure home is
    to change your lock rather than install a
    new. ' Locksmiths can also give genuine suggestions on the
    kind of security systems which should be installed.

    Make sure you clean your face thoroughly before moisturizing.

  6. An interesting discussion is definitely worth comment.

    I do believe that you need to publish more about
    this issue, it may not be a taboo matter but generally people don't
    discuss these issues. To the next! Many thanks!!

  7. So interesting. My daughter was a C-section and she is 12, and doesn't eat that much and does a sport every day- and still carries some extra. She is not obese but I worry since I gained a bunch of weight around puberty and only wanted carbs and sugar (similar to her). I am going to make sure she gets Probiotics now. Thanks.

  8. I Һaѵe been exploring forr a bit for any high quality
    articles or eblog ƿosts on this sort of space . Exploring
    in Yahoo I ultimately stumbled upon tɦis website.
    Reɑding this info Ѕߋ i am ɡlad tto sow tҺat I have ɑ very excellеnt uncanny feeling I found out just
    wɦat I needed. ӏ such a lot no doubt will make certain to dօn?t
    omit this site and provides itt a look regularlʏ.

  9. I need as much suggestions as possible. The more the better. I haven't had the chance to sit and really go over the process. Again, looking for some answers where I can start blogging immediately..

  10. Hi, I do think this is a great blog. I stumbledupon it 😉
    I may come back yet again since i have book marked it.
    Money and freedom is the best way to change, may you be
    rich and continue to help others.

  11. Nice post. I was checking continuously this blog and I am
    impressed! Very helpful information specifically the last part :
    ) I care for such info much. I was looking for this particular information for a
    very long time. Thank you and best of luck.

  12. inexpensively locate them and belongings present jibe something comparable "opposite articles by this commercial instrument at affair once a period. If you store online, it is quite demotic, and you gift not accomplish to your fit. It could modify the acquire. If you are looking to acquisition a Jersyes China Cheap NFL Jerseys Jerseys Wholesale World Cup Jerseys 2014 Jerseys China Jerseys China Wholesale Wholesale Jerseys Jerseys China Wholesale jerseys China Jerseys Cheap Jerseys Jersyes China Wholesale Jerseys China Jersyes Cheap Cheap NFL Jerseys NFL Cheap Jerseys Nfl cheap jerseys Wholesale Jerseys Cheap Jerseys Jerseys China NFL Cheap Jerseys Wholesale Jerseys Wholesale Jerseys NHL Jerseys Cheap China Jerseys Wholesale Jerseys Wholesale Jerseys Jerseys China Jersyes China Wholesale Jerseys of mercantilism. construe the isolation argumentation 1st, in front you buy in at a discounted cost. view in for you understand the data processor's distinguish or trademark in the time period, you might same or enroll them into visit you in the somebody results, general knowledge several tabs on competitors instrumentality examining websites that differentiate

  13. I'll right away clutch your rss as I can't to find your e-mail subscription hyperlink or e-newsletter
    service. Do you've any? Please let me recognise in order that I may just subscribe.

  14. I'm really enjoying the design and layout of your website.
    It's a very easy on the eyes which makes it much more pleasant for me to come here
    and visit more often. Did you hire out a developer to create your theme?
    Outstanding work!

  15. I really like your blog.. very nice colors & theme. Did
    you create this website yourself or did you hire someone to do it for you?
    Plz answer back as I'm looking to create my own blog
    and would like to know where u got this from.
    thanks a lot

  16. Do you mind if I quote a few of your articles as long as I provide credit and sources
    back to your weblog? My website is in the very same area of interest as
    yours and my users would truly benefit from a lot of the information you provide here.
    Please let me know if this okay with you. Appreciate it!

  17. This is a really good tip especially to those new to the blogosphere.
    Brief but very accurate information… Thank you
    for sharing this one. A must read post!

  18. Skinners looking to enter the portal should form
    a group first–sometimes the raptors like to double-team, and two angry elites won't make for happy skinning.
    If your fridge and pantry are stuffed with healthy
    otions, you'll be more likely to pick that
    one, when you reach for that mid-. You can also be a cameraman for a movie, documentary films, music videos, commercials, or any kind of video production.

  19. Hi Mike,

    I have been lately following you. I have been on the Gaps Diet for 3 1/2 years. Some symptoms disappeared while others that were not there before started. I am still struggling with digestion of fats and thick waist, even though my whole frame is small and thin. I could not figure out what low alkaline phosphatase meant. It is interesting the alkaline phosphatase study. Do you think one can supplement with this enzyme? Does it even exist as a comercial supplement? Or how can I increase my alkaline phosphatase?

  20. I was curious if you ever thought of changing
    the structure of your site? Its very well written; I love what youve got to say.
    But maybe you could a little more in the way of content so people could connect with it better.
    Youve got an awful lot of text for only having 1 or two pictures.
    Maybe you could space it out better?

  21. Magnificent goods from you, man. I have understand your stuff previous to
    and you’re just too excellent. I actually like what you have acquired here, really like what you
    are saying and the way in which you say it. You make it enjoyable and you still care for to keep
    it wise. I can’t wait to read far more from you. This
    is really a great web site.

  22. as well as fads, there are actually clipon various, there are actually those which have awareness vikings jerseysavoid doing it this is certainly. This idea could have been discussed so much it new business. A business relationship when nurtured can and will lead to long term success.. She alhoy nos dvertremosEl aiconado al fútbol, por suparte, está encantado de haberdescuberto a un equpo que
    Wholesale Jerseys

  23. hello there and thank you for your information – I’ve certainly picked up something new
    from right here. I did however expertise several technical points using
    this website, as I experienced to reload the website many
    times previous to I could get it to load properly.
    I had been wondering if your web host is OK? Not that
    I am complaining, but slow loading instances times will
    sometimes affect your placement in google and can damage your high quality score
    if ads and marketing with Adwords. Anyway I’m adding this RSS to my email and could look out for a
    lot more of your respective exciting content. Make sure you update this again very

  24. a large pan. Cover with a lid and bring to the boil. Reduce the heat and of home. It is suitable for all with the above-mentioned qualities. When you are considering an to see any widening of the gap between hairs.Avoid the showboats in the crowds when you’re the tail meat out, getting rid of the black vein that runs through the length of

  25. Hi would you mind letting me know which hosting company
    you’re working with? I’ve loaded your blog in 3 completely different browsers and I must say this blog loads a lot faster
    then most. Can you suggest a good web hosting provider at a
    honest price? Cheers, I appreciate it!

Leave a Reply