Scientists in Italy recently discovered individuals with higher waist circumference and elevated blood pressure had reduced levels of antibodies for SARS-COV-2 virus after their two-dose immunization. We discuss this study and the CDC's recent report noting vaccine effectiveness (VE) has declined from 91% to just 66% in recent months as motivation to include nutrition and healthy living into the “staying safe” conversation!
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Related: Obesity & COVID are Interconnected: a Call to Action to Address this Epidemic
00:15 Individuals with a higher waist circumference had a reduced level of antibodies for SARS/COVI2 virus, in a study of European healthcare workers.
00:35 Vaccine effectiveness has gone down from 91% to now 66%, according to the CDC’s Morbidity, Mortality Weekly Report (MMWR).
01:40 Central obesity, smoking habit, and hypertension are associated with lower antibody titers in response to COVID 19 MRNA vaccine (Pfizer). This is from a study of 86 healthcare workers in Italy. (Watanabe et al 2021)
02:35 Antibody titers will naturally go down after any immunization.
02:50 T-Cell immunity may last longer than antibodies. Both are part of your adaptive immune system.
03:35 Your metabolic and immune health impact your body’s immune response to any immunization.
04:40 Between 20% and 30% of normal weight people are metabolically obese. 63% of study participants had normal weight, but 60% had an obese waist circumference.
05:35 Patients with higher waist circumference had significantly lower SARS COVI2 antibody titers. Obesity, defined as a BMI greater than 30 kilograms/meter squared, was not associated with lower SARS/COVI2 antibody titers. It was specifically related to the quantity of fat and waist circumference.
06:50 Smoking and high blood pressure are linked to a sub-optimal immune response to immunization.
07:50 We need to exercise. Pre-outbreak, only 30% of adults met physical activity requirements and 25% of children met their daily and weekly energy expenditure and physical activity requirements.
11:10 If you want to get the protective effects of immunizations, you need to be getting exercise, eating real food, managing your stress, and prioritizing sleep.
11:45 Hypertension is linked to an inappropriate response to vaccinations and may have a common root to a dysfunctional immune system. It is linked to worse COVID19 outcomes.
12:15 High blood pressure is an immune stressor.
12:35 Sleep is one of the best things you can do for blood pressure. Exercise is the second next best thing for blood pressure. Try doing 3 each 10-minute walks per day.
14:11 Age and smoking predict lower antibody titers at the 3 months after second dose. There were higher antibody titers in women than men.
15:15 Smoking cessation before vaccination may improve individual vaccine efficacy.
17:10 Delta variant infections were higher in the fully vaccinated study participants.
(Watanabe et al 2021) Watanabe, M., Balena, A., Tuccinardi, D., Tozzi, R., Risi, R., Masi, D., et al. 2021 . Central obesity, smoking habit, and hypertension are associated with lower antibody titres in response to COVID-19 mRNA vaccine. Diabetes/Metabolism Research and Reviews, e3465. http://doi.org/10.1002/dmrr.3465
Fowlkes, A. (2021). Effectiveness of COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Frontline Workers Before and During B. 1.617. 2 (Delta) Variant …. Cdc.Gov http://doi.org/10.15585/mmwr.mm7034e4