Exercise has been shown to benefit autophagy via a two-pronged approach:
1) Exercise is a direct autophagy enhancer (at least in muscle tissue).
2) People who regularly exercise have increased autophagy when they fast.
Dethlefsen, M., Bertholdt, L., Gudiksen, A., Stankiewicz, T., Bangsbo, J., Hall, G., Plomgaard, P., Pilegaard, H. (2018). Training state and skeletal muscle autophagy in response to 36 h of fasting Journal of applied physiology (Bethesda, Md. : 1985) 125(5), 1609 – 1619. https://dx.doi.org/10.1152/japplphysiol.01146.2017
Autophagy Deep Dive with Peter Attia, MD:
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Before you open up that bag of chips (out of boredom) have an ‘Exercise Snack’. As the dotted lines in the image above show, a small exercise snack lowers glucose and insulin and has additional benefits for fat mobilization and mental clarity 🔥🔥. P.S. @stanefferding @marksmellybell have been promoting this for a loooong time! #fitness #fatloss #10minwalk #hiit #snack #exercise #exercisesnack #exercisescience