Seed Oil

The Detrimental Impact of Seed Oils on Your Health: Headaches, Joint Pain, Fat Cell Inflammation and More

by Mike Mutzel


New details are emerging about the health problems linked with seed oils consumption.


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 Research Cited

1.Kris-Etherton, P. et al. Polyunsaturated fatty acids in the food chain in the United States 1 , 2. Am. J. Clin. Nutr. 71, 179S-188S (2000).

2.Warner, D. R. et al. Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice. Am. J. Pathol. 187, 2232–2245 (2017).

3.Boyd, J. T. et al. Elevated dietary ω-6 polyunsaturated fatty acids induce reversible peripheral nerve dysfunction that exacerbates comorbid pain conditions. Nat. Metab. 3, 762–773 (2021).

4.Sanders, A. E. et al. Circulating Omega-6 and Omega-3 Polyunsaturated Fatty Acids in Painful Temporomandibular Disorder and Low Back Pain. J. Pain 23, 1724–1736 (2022).

5.Ramsden, C. E. et al. A systems approach for discovering linoleic acid derivatives that potentially mediate pain and itch. Sci. Signal. 10, (2017).

6.Guyenet, S. J. & Carlson, S. E. Increase in Adipose Tissue Linoleic Acid of US Adults in the Last Half Century. Adv. Nutr. 6, 660–664 (2015).


Show Notes:

00:00 Linoleic acid oxidizes easily.

00:50 Linoleic acid is stored in your fat tissue with a half life of over 680 days.

01:40 25% of total fatty acids in your fat cells comes from linoleic acid.

02:30 Soy, cotton seed, canola, and sunflower oil are in most processed foods.

03:05 Pain can be influenced by chronic seed oil consumption.

05:30 Adipose tissue linoleic acid has doubled.

06:00 We are eating less beef, pork, butter, and lard, and more chicken and seed oils.

07:25 Adipocytes become inflamed.

08:10 Inflammation from fat worsens metabolic health.

09:20 Oxidation of lipids in LDL is a major risk factor for coronary heart disease.

10:20 High intake of omega 6 fats from seed oils is associated with depression and poor mental health.

12:00 Omega 6 fat is liked to persistent pain, headaches, irritable bowel, low back pain, and rheumatoid arthritis.

12:45 Omega 3 fats are linked with reduced pain.


  1. What do you suggest I use instead of seed oils? I have clarified butter and cocoanut oil (would that be considered a seed oil?)

  2. Butter (imo), coconut oil, avocado oil, and olive oil are all great. I’ve heard some good things about rendered duck fat and some people even favor lard over seed oils. But the duck fat and lard are both things I’d like to find out more info on before actually bringing them into my life.

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