Immunity

Omicron’s Mutations: Scary or Signal Beginning of the End

by Mike Mutzel

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Let's discuss the potential good news with regards to the recent variant of concern and how these mutations can lead to reduced severity of illness that's easier to catch.
 

 

 

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Episode Time Stamps:

0:00 Intro
0:45 Transmission VS Virulence Trade off
1:30 New mutations, what they mean
3:42 Location of ACE2: why it matters
4:31 Most important point of this paper
5:53 Testing Vitamin D at home
6:23 Details of the new mutations and ACE2
7:42 Upper airway infections are easier to transmit, catch
8:14 The transmission VS virulence trade off
9:52 ACE2 receptors have gradient densities in the airway
10:50 I could be wrong!

 

References Cited:

Vu MN, MenacheryVD (2021)Binding and entering: COVIDfinds a new home.PLoSPathog17(8):e1009857.https://doi.org/10.1371/journal.ppat.1009857

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