NAC (N-acetyl cysteine) & Glutathione Update | Don’t Freak Out Just Yet

by Mike Mutzel




What's the fuss about NAC (N-acetyl-l-cysteine)?

When Amazon recently announced they were removing listings of the dietary supplement N-acetyl-l-cysteine, or NAC, from their website health seekers started stockpiling it as though it was toilet paper from March of 2020.

I personally think these emotional purchases are unjustified, as NAC has been used since the 1960s, has an excellent safety record and is actively being studied in over 100 clinical trails. (1) There's ambiguity around the ingredient because it was initially approved by the FDA for inhalation delivery systems, not as an oral agent. (2) Since Amazon has been actively trying to clean up their dietary supplement listings (which I think is good and necessary), they likely sought to avoid any potential FDA scrutiny and axed all NAC listings out of an abundance of caution.

Since NAC has a long safety record and has been used for years as an antidote against TYLENOL (acetaminophen) intoxication, I doubt it's going away.

Related: This NAC + Glycine Powder is a unique and effective blend.

What Are the Health Benefits of NAC?

NAC is a precursor to L-cysteine and has been shown to increases the synthesis of glutathione (GSH), the body’s most abundant antioxidant and compound that's involved in detoxification.

In the related video, we discuss more about:

-Potential health benefits of NAC

-Why taking NAC at night is best

-Other synergistic amino acids that can help NAC make glutathione

-Why you shouldn’t be stockpiling NAC!

-Related NAC science and applications




  1. Clinical
  2. CRN: ‘This is not the final word on NAC’

  3. Mokhtari V, Afsharian P, Shahhoseini M, Kalantar SM, Moini A. A review on various uses of N-acetyl cysteine. Cell J. 2017; 19(1): 11-17.

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