Ketones Have Anticatabolic Properties in Muscle Tissue: Implications for Fasting and Exercise

 

 

Ketones & Muscle Loss—New Data

Strategies that can prevent age-related muscle loss are hot topics among scientists nowadays.

In this video we review new research suggesting that ketones have “anti-catabolic” effects in muscle—meaning: they may slow muscle loss.

Links to Studies Mentioned:

Koutnik, A. P., D’Agostino, D. P., & Egan, B. (2019). Anticatabolic Effects of Ketone Bodies in Skeletal Muscle. Trends in Endocrinology & Metabolism, 1–3.

Nutritional Tools People Find Helpful:

Berberine HCL + ALA Complex | 500 mg of Berberine Per Serving

Ketone + MCT MicroDose | Exogenous Ketone w/Medium Chain Triglyceride to Boost Ketone Production

Tweets and Social Media Commentary:

New review about potential anticatabolic effects of #ketones in muscle by @AKoutnik @DominicDAgosti2

Link: https://t.co/gRRKgyMoTe pic.twitter.com/8XSPaVgvFC

Related Discussion: Slowing Muscle Loss, Cachexia and Muscle Growth Strategies w/ Andrew Koutnik, PhD

— Mike Mutzel, MS (@MikeMutzel) February 5, 2019

 

The implications are for pathological situations like cachexia where training may not be an option. Or where the goal is to attenuate the catabolic signals

— Dominic D'Agostino (@DominicDAgosti2) February 6, 2019

 

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Increasing Muscle Protein Synthesis (MPS) is all the rage nowadays. But instead of guzzling down protein every few hours to drive MPS, maybe you can just stay in ketosis, instead….. ——————————————— Over the last thirty years several labs have shown that ketones can curb inflammation associated decreases in muscle cell anabolism. (e.g. ketones are anticatabolic.) This new review published by Andrew Koutnik & @dominic.dagostino.kt explores some new mechanisms and details about how ketones influence the anabolic balance in muscle tissue. Cool stuff, eh? #bcaa #keto #ketogenicdiet #ketodiet #ketogenic #ketoaf #muscleprotein #postworkout #preworkout #legday #squats #intermittentfasting #timerestrictedeating #metabolichealthsummit

A post shared by Mike Mutzel, MS (@metabolic_mike) on Feb 5, 2019 at 1:33pm PST