Ketogenic Diet

Jillian Michaels Trashes Keto, Badly Botches The Nutritional Science

by Mike Mutzel




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Key Time Stamps and Takeaways


n01:08 Ketones made by your liver affect your body metabolically and epigenetically. It is like a software update for your metabolism.

01:55 You can get into ketosis with low carb diets, exercise, fasting or time-restricted feedings.

03:00 Autophagy is part of being in a fat-adapted state.

03:54 Ketosis is not starvation.

05:02 It is difficult to burn body fat for fuel when we eat 5 or 6 times a day and have an extended feeding window.

06:04 Burning fat for energy is more efficient than burning carbs, producing less metabolic and oxidative stress.

07:07 The ketogenic diet mimics the metabolic effects of calorie restriction: glucose deprivation, reduced insulin and IGF1 signaling, reduced mTOR signaling.

07:20 The diet is linked with less incidence of cancer, neoplasm and growths, as well as less chronic inflammatory disease.

07:53 Calorie restriction causes adaptive thermogenesis, the decrease in the body’s resting metabolic rate.

08:18 The resting metabolic rate from the ketogenic state or calorie restriction is not depressed in the post-weight loss window.

09:09 Ketosis is better for your liver. When you eat a lot of carbs, your liver undergoes de novo lipogenesis (DNL) and accumulates fat.

09:43 In ketosis, your liver takes fat from the liver and makes ketones.

09:55 Fat burning preserves the NAD/NADH ratio. It preserves your cellular battery.

12:44 The ketogenic diet includes high polyphenolic fruits and vegetables.

14:49 Our cell membranes are mostly fat. Omega 3s enhance the fluidity of your cell membranes.

  1. Thank you for your articulate explanation. It is very pleasing listening to you and I agree wholeheartedly with your perspective. Perhaps Jillian is responding to her ulterior motive concerning her sponsors.

  2. Very much enjoyed this podcast. Thanks. Can you provide the link for that study out of the Colorado Med School (about RMR from CR vs TRF)..

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