Low Zinc, Low Testosterone: Science You Should Know

by Mike Mutzel


Zinc is an essential mineral involved in over 200 enzymatic reactions. Science shows it may help support hormonal health in men.




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Prasad, A. S., Mantzoros, C. S., Beck, F. W. J., Hess, J. W. & Brewer, G. J. Zinc status and serum testosterone levels of healthy adults. Nutrition 12, 344–348 (1996).

Santos, H. O. & Teixeira, F. J. Use of medicinal doses of zinc as a safe and efficient coadjutant in the treatment of male hypogonadism. Aging Male 23, 669–678 (2020).


Time Stamps:


00:30 Zinc supplementation can increase Testosterone levels.

01:55 Zinc is an essential nutrient that plays many roles.

02:10 Testosterone is an androgen that plays many roles.

02:35 Zinc deficiency leads to structural changes within testicles and impairs testosterone synthesis.

04:00 The conversion of testosterone to its active form requires 5 alpha reductase, which is dependent upon zinc.

04:30 Zinc deficiency may lead to decreased male hormone receptor activity.

05:30 Mike recommends zinc bisglycinate chelate bound to glycine.

07:30 Zinc is lost in sweat and ejaculate.

09:30 Consider your zinc-copper ratio.

09:58 Low testosterone increases risk of cardiovascular disease, depression, cerebral vascular disease, insulin resistance, and increased belly fat.

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