Restore Your Hormones Through Improved Insulin Signaling
With Corey Schuler, MS, DC, LN, CNS, CNP, FAAIM
Dr. Schuler both a locally and nationally recognized expert in the field of natural health and metabolism. He is a frequently sought out expert teaching to physicians and other healthcare providers, often interviewed for radio and magazines, and consulted by leaders in the industry.
He is the founder and director of Metabolic Treatment Center in Bloomington and Eagan Minnesota.
03:18 Dr. Schuler’s Story: Dr. Schuler was teaching young men about healthy living. He realized that he had little actual knowledge. Before he started chiropractic college, he went to a seminar by Jeff Bland, the father of Functional Medicine, on the effects of vitamin D. That was his start.
06:12 Testosterone: Often testosterone testing shows that we are within the reference range. However, the reference ranges are vast. Testing hormones in perimenopause is worthless. Women can have 10 -15 different spikes or troughs in their hormones in a single day. Diabetes has a direct negative impact upon testosterone. Testosterone may not decline with age if you pull out the obese and diabetics from studies.
12:01 First Line of Treatment: In a male patient with low testosterone, obesity and diabetes, first treat the insulin resistance. When the cell stops responding to the only hormone that gets blood glucose into the cell, we need to do something different.
12:50 Improving Insulin Function: Supplements will not help if there are no dietary changes. Because of genetics and/or lifestyle, some people have to work incredibly hard to be moderately healthy. A low carb diet with relatively high fat and moderate protein is used for insulin resistance. Ketogenic diet will also work. However, Dr. Schuler sees that some people cannot handle the mood changes that accompany the diet.
14:24 Berberine: Berberine (500 mg 3 times/day) has outperformed Metformin in a few trials. Berberine has been found to be supportive and antimicrobial, even at tiny doses. Unlike antibiotics, it does not have a complete and direct impact on killing the microbes. It makes the gut uncomfortable for habitation.
15:43 The Gut: The gut is pivotal axis in health. It is an extremely complicated interface with our environment.
16:44 Melatonin: It has 2 primary receptors, MT-1 and MT-2. It is 3 billion years old, one of the oldest things in our bodies. Pharmacology is trying to improve half-life and manipulate binding. Don’t mess with something that is 3 billion years old. It is smarter than we are. Melatonin impacts many pathways. It has been studied for 20 years. For sleep, a study of aging adults found that .1 mg 30 minutes before bed was relatively ineffective inducing the sleep cycle. With .3 mg, people had hypothermia and circulating melatonin levels the next day. Dr. Schuler prefers .3 mg for jetlag and shift work. Very high doses help with the destruction of cancer cells. In non-time released melatonin, in 50 minutes you have metabolized half of your dose. High doses should be taken earlier due to impacts upon the pineal gland.
24:58 Adrenals and Circadian Rhythm: Cortisol is not an enemy. Cortisol can be a marker for adrenal dysfunctions.
26:06 11 Beta Dehydrogenase: It is an enzyme that converts cortisone to cortisol. We need to look at more than salivary cortisol panel.
27:48 Adrenal Fatigue: It is caused primarily by circadian and biological rhythm maladaptation. Having one tissue fail while the rest of our body tissue is healthy makes no sense.
28:53 Epigenetic Expression of Clock Genes: Even knowing our genes is not enough. We need to know the influences. Every cell in our body has these clock genes.
30:03 Circadian Rhythm Strategies: Determine sleep quality. If you don’t sleep, you don’t heal. While you sleep, growth hormone increases. Acetylcholine is more prevalent. Mitochondria oscillate in a circadian rhythm, being more active at night and burning fat.
32:57 Testing: The more data we have, the more we can do. Stay with the same labs. Annual testing is beneficial, but Dr. Shuler recommends quarterly testing for people who are sick. This helps us understand our annual rhythms.
34:15 Dr. Schuler’s Ebook: Balancing Hormones in an Unbalanced World talks about the remote effects of hormones. It also helps you to deal with your clinician.
35:46 Dr. Schuler’s Favorite Supplement: Curcumin has many medicinal uses.
36:20 Dr. Schuler’s Lifestyle Tip: Do yoga and give hugs. The release of oxytocin from touching someone you love/like is beneficial. Yoga improves breathing, flexibility, mindfulness, reduces impact on the HPA, and improves sleep.