Cardiovascular disease

High LDL But Zero Plaque: Surprising Study of Metabolically Healthy People

by Mike Mutzel

0 comments

New research shows that high LDL cholesterol is not independently associated with coronary artery calcification in metabolically healthy individuals, challenging long-held beliefs about heart disease risk.

 

Sponsored Message:

Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator by MYOXCIENCE:  Use code podcast to save 12%

Research Mentioned:

 

Budoff, M. et al. Carbohydrate Restriction-Induced Elevations in LDL-Cholesterol and Atherosclerosis The KETO Trial. JACC: Adv. 3, 101109 (2024).

 

Time Stamps:

0:00 Intro

0:20: LDL cholesterol: new study

0:51: Approximate the degree or severity of atherosclerosis…

2:00: Metabolically healthy people and high LDL

2:59: I think the median LDL

3:52: Tools to support your metabolic health…

4:40: You can start your fast and have a better night's sleep. And you can also take it in the morning on an empty stomach…

5:37: We can see if there are elements of their lifestyle that confound the study results. And in this case, there are confounding variables…

6:37: And the triglycerides are the same. They're about 45% lower in the keto group. The average triglyceride level here, the median, was 64 mg/dL…

7:36: And remember, their LDL cholesterol was about 50% lower. So why is that? They say in the subset of the keto subjects…

8:33: There was no significant difference in the stenosis score when you compare the different groups. And there were no significant differences…

10:01: And so they say in conclusion, coronary plaque in metabolically healthy individuals with carbohydrate restriction-induced LDL cholesterol levels…

10:53: So what do we make of this? What do we do? And this may take another decade or maybe two decades for the medical community to actually adopt…

Leave a Reply