Stu Freedenfeld

Stu Fredenfeld, MD

Safe and Effective Whole Body Detoxification Strategies

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[text_block style=”style_1.png” align=”left”]Dr. Schwartz: Welcome everybody to the Autism Intensive. We are very fortunate to be here with a friend and brilliant colleague, Dr. Stu Freedenfeld. Thanks so much for being with us, Stu.

Dr. Freedenfeld: Thank you for inviting me.

Dr. Schwartz: And I just want to say a few words to give us some background for our listeners and viewers. Stu has graduated with honors from the College of Medicine and Dentistry of New Jersey. Then he went into residency in family practice and went on his own when he learned that there was more to medicine than what you were taught in medical school. Currently clinical professor at Rutgers and works with integrating a wide variety of techniques to his medical practice. Recently he has focused on autism, and detox and environmental medicine connection. Why don’t you say a few more words about what you actually do in your clinic and modalities that you find useful? And then your interest in autism, which you focused on and how the environmental connection is a factor.

1:00 Dr. Freedenfeld’s Practice

Dr. Freedenfeld: Sure. So I have got a very eclectic practice. I’ve started as a family practitioner. I’ve done obstetrics. I’ve delivered over 500 babies in my career. I still love handling the full spectrum of family practice with a holistic integrative orientation. I have also developed a wide variety of special interests, special skills in dealing with autism, ADD, ADHD, autoimmune diseases, cardiovascular diseases, neurodegenerative diseases, gastrointestinal diseases, muscular-skeletal, etcetera. It’s been a big wild trip.

Dr. Schwartz: Right, Well you’ve been an innovator and not afraid to push the boundaries and go outside the box. I’ll certainly acknowledge you for that. I’m sure your patients do, Stu.

Dr. Freedenfeld: I’m not sure I know where the box is.

Dr. Schwartz: You’ve expanded it. I was reading your website, which we will reference, for the listeners, but to enjoy your background and ability to be a life-long learner.

Dr. Freedenfeld: Oh, indeed. It’s the joy.

Dr. Schwartz: But as far as what modalities do you use in your clinic and then what do you find helpful in autism and how does detox?

02:25 View of Traditional Medicine

Dr. Freedenfeld: As you can imagine, we use it a whole lot since we treat a very wide range of disorders. I think the first and most important skill of the healer is to listen to the patient, to develop a clear understanding of what they are dealing with, how it started, what was going on before it started. How has it impacted their life, and to develop an understanding of what we need to do to reverse that. There is too much of a tendency in conventional medicine to draw a line between disease and treatment. It’s almost like that game we had in grammar school where we would draw a line between the desk and the chair and the horse and the buggy. But in this case, it is between bronchitis and the antibiotic, between hypertension and whatever anti-hypertensive drug. It’s just disease/drug, disease/drug. And I often lamented the fall of medicine into an exchange of paper. You give me a green piece of paper and I give you a blue piece of paper. It is really sad, where our education is being driven by pharmaceutical reps who learn on a weekend seminar what to tell you about their new drug and why it is better than the last drug that is going off patent. It’s just sad.

Dr. Schwartz: That’s just sad but true in the amount of time per office visits that prescription pad medicine is very compelling.

Dr. Freedenfeld: Absolutely, because there’s no time to do anything other than identify horse and chair and horse and buggy.

Dr. Schwartz: But again, I acknowledge that you’ve been able to build a new model. And I know that you have other practitioners in your clinic. And one is a mom who has recovered 2 children with autism. So hopefully we’ll be able to talk with her. But as far as how did you get into the detox end and how would you evaluate someone for toxicity on the spectrum and, of course, this applies to everything else.

04:37 Introduction to Alternative Medicine

Dr. Freedenfeld: So my interest. I’ve always had interest in kind of a different edge when I treat people because it is just my nature, I guess. But, I never had a direction to that edge. One day in my career, a few years into it, a young doctor knocked on my door, literally, and said “I’m graduating my residency. I am looking for a place to join a family practice program in this area, would you be interested?” I was swamped. I cleared the desk in front of me and said ”Have a seat.”

Dr. Schwartz: So good synchronicity. Did you know this person?

Dr. Freedenfeld: I had never met him before. But you know. You feel energy from people. You know that he is a good spirited individual. And far more than I ever expected. He told me “Oh, by the way, I do acupuncture and homeopathy and traditional Chinese herbs. Would you mind if we did that?” I said “Oh that sounds great. Let’s bring it on. Teach me.” But the traditional teaching is in an energetic dialogue and my science brain does not quite speak that language well. I could speak it, I really felt like I was speaking in French, trying to read poetry in French. It never really resonated with me.

06:03 The Paradigm Shift

Dr. Freedenfeld: After a while, 3 of my patients in one year suffered consequences from cardiovascular investigations. These were all for evaluations. Two had angioplasties. One died on the table. The other one died a week later. A third one had a terrible infection. She was in her 80s and had a terrible infection in her groin and it took a year for it to clear up. And I said “You know, there has got to be something else. There has got to be something different.” I had heard about this thing called chelation. Went off to a conference with ACAM, the American College for the Advancement of Medicine. I spent 3 days learning about chelation and was just blown away with the level of really clear science-based information on what this is doing. And I stayed for the 3 day conference, which for the first time in my medical career, was given by scientists, by the researchers, not by the doctors who were writing articles for the pharmaceutical industry. And all they wanted to do was share their information. We were talking about magnesium and Coenzyme Q and carnitine. It was a cardiovascular conference and I thought “Oh, my Gosh. These are the things we talked about in the first two years in medical school. This is the basic physiology, not the pharmacology. The physiology, the biochemistry of the body. How can we manipulate that to help the body heal itself? Not take a drug to block it so that it looks like it’s healing itself. How do you do it? ” It was just phenomenal.

Dr. Schwartz: So you were just drawn to that real learning and real science and real medicine and that helping.

Dr. Freedenfeld: It just can’t end. Once you get that taste, you can’t stop.

Dr. Schwartz: Wonderful, Stu. From my experience, that is true from you totally. And I have been in your clinic and observed how your patients appreciate that and come from all over to see you and have access to that depth and level sort of thing. Tell us how you got in the autism realm and what you see helpful for the kids.

08:22 An Introduction to Autism

Dr. Freedenfeld: That is a bit of a funny story. A young mom came to my office one day and said “I hear you are an open-minded doctor. You do a lot of unusual things. Can you help my child with autism?” Now understand, when I was learning autism, there were 6 kids in New Jersey that had autism. We did a fieldtrip to see them in a ranch house that was corralled off and they sat in these little corralled off area with a bunch of balls rolling around. That’s what we were told that this was a form of childhood schizophrenia, and the refrigerator mom story. My understanding of autism was zero. I said to her “Okay, what can I do?” So she reached into her bag and pulled out this stack of papers and put them on my desk and said “Here. Read this.” I said “Thank you”, a real stack. And I did.

Dr. Schwartz: With the open mind ready to learn new things?

Dr. Freedenfeld: Well, and what we’ve learned being part of the Autism Research Institute and part of the Think Tank where we have really brought brilliant minds. I don’t consider myself a brilliant mind. I’m a practitioner. I do what the brilliant people teach me. Being in the room with these brilliant people and sharing their understanding of biochemistry and learning about what we do to fix the problems that have afflicted the autistic children, expands what we do for everybody else. That’s just really one body biochemistry.

10:05 The Refrigerator Mom Theory

Dr. Schwartz: Sure, and the thing that I was going to go back to, some of our viewers and listeners be familiar with that term “Refrigerator Moms”, so just say a word or two about that.

Dr. Freedenfeld: There was a…I’m blanking on his name. Maybe you can help me.

Dr. Schwartz: Bruno Bettelheim

Dr. Freedenfeld: Yes, Bettelheim, who was purported to be a psychologist. It actually turned out he wasn’t a psychologist. But he wrote a treatise on the cause of autism. He blamed parents. So it was a cold and indifferent mother that created a schizophrenic child.

Dr. Schwartz: So autism was blamed on the mom.

Dr. Freedenfeld: Of course.

Dr. Schwartz: And that’s probably what I learned in medical school, something along those lines. So here’s a mom, desperate for help. Coming to the doc that’s open-minded. You read the literature, the references and what did you think? How did you?

11:00 Dr. Freedenfeld’s Autism Involvement

Dr. Freedenfeld: Oh, I started reading it. Maureen McDonald, who a lot of people will know the name from Autism Research Institute and the DAN conferences, was a good friend and I can I say, she has been a patient of mine. She had been encouraging me to get involved with autism. My practice was so full that I really didn’t feel that I had time to expand out, but now with this young mother, I said “Okay, let’s do it.” ‘cause I never say no to people. I always find a way to help them. I was invited to the original Think Tank down in Texas. I started going to the DAN conferences in Philadelphia, in Cherry Hill, I think. And got more and more involved in it and it’s been another wonderful trip.

Dr. Schwartz: Great. And you’ve been involved in the Think Tanks, and you’ve been into that wonderful thing and I’ll refer our listeners to that wonderful thing to that interview with Sid Baker’s about Dan got together with John Pangborn.

Dr. Freedenfeld: Yeah. That’s a wonderful experience.

Dr. Schwartz: So that was very fascinating and I was involved in that later on, but that wonderful spirit of bringing together parents, clinicians and researchers to try to make a difference. I know in conferences one of your areas of course is environment and detox. So was it a gradual processes where you started seeing a few kids and then learning more and?

12:35 How Can We Prevent Autism?

Dr. Freedenfeld: At the DAN conferences, we were talking about what we knew. We knew that gluten and casein were a problem and we’re teaching diets. We knew about the funny reaction that we would get when oxytocin infusions. And we began learning more and more about methylation and sulfation defects. And we were really focused on how to treat the kids, very important, how to treat the kids. Wait a minute. We were in the middle of this autism epidemic. More kids are being afflicted. Don’t we want to take one step back and what can we do to prevent it? To stop it from happening, not just treat the ones that are affected. So as I was preparing this talk, I had to go into the literature to see what might be causing this. What toxins were in our environment? It was very clear that autism is not caused by genes. It is not an inherited trait, but yet, it is expanding. What in the environment was causing this? It had to be something environmental.

 

 

13:51 Are Genes the Cause of Autism?

Dr. Schwartz: Can I just interrupt you right here, Stu, because this is a huge controversy. People are still saying that we are better at recognizing it. And we are still doing a tremendous amount of research on genes now. Can you expand and share your thoughts on those because I still won’t hear how that from college professionals.

Dr. Freedenfeld: So, genetically, our genes that become prevalent become prevalent because there is a benefit to them. Even something like sickle cell trait. The sickle cell gene only became prevalent because there is a selected advantage against malaria in people who have the sickle cell trait. The diseased people, they still suffer, but the people with one gene, not two genes for sickle cell live longer. So in an environment where sickle cell disease is prevalent, they have an advantage. They are more likely to live to the age of maturity to have babies and pass on the gene. Our genes are propelled if they help us in our environment.

Dr. Schwartz: There are very few bad genes.

Dr. Freedenfeld: There are genes that are, where we have these variations polymorphisms in genes. But these are selectively beneficial in different environments. So it is like preparing the species for the next environmental change. As the environment changes, those who have this genetic makeup are more likely to propel forward. And that becomes selectively prominent. In the human species, it is a little different because we keep unhealthy people alive. And I’m not saying we shouldn’t. But as far as the normal biology, people who are weaker, less able to be healthy in this environment, in other species, would disappear. So the species becomes stronger and stronger. With respect to the autistic children, there are a number of different varieties of each gene. And each of those genes may be selectively disadvantageous in a toxic environment. They might be selectively advantageous in a pristine environment. As our environment becomes more and more toxic, we are seeing more and more kids become afflicted by the effects of these environmental toxins.

Dr. Schwartz: This is really a deeper assessment and analysis. Which, I will say, unfortunately, that modern medicine does not get into very much. Hyper-focused on the genes is not very productive.

Dr. Freedenfeld: Well, it’s the latest greatest. It’s like the whale watchers. Let’s go run and look at the genes. But the genome is not giving us the kind of information that we thought it would. It’s not even telling us even what the best pharmaceutical is, because there is so much more to how a gene expresses itself than just the gene makeup. So there are influences from the environment on whether the gene is expressed or not, on whether it is turned on, turned off.

Dr. Schwartz: And then the individual, what we call biochemical individuality. So can you talk about that and how you assess that and what kinds of toxicities you do find in the kids?

17:32 We are Pouring Toxins into our Bodies

Dr. Freedenfeld: Let me go back. I just want to talk about that initial talk that I developed, because it really became my source of education. I just didn’t understand what was going on. So as I started looking for where these sources were, we started looking at the stuff in our home. Not so much the smokestacks. Because those are things we can’t control, at least not as an individual. But we can control what we bring home. We can control what our food is contained in. What the health of our food is. What our upholstery, our carpets are made out of. What kind of fluids we use to clean our home. And when I looked into the research, it was amazingly solid research that we are pouring toxins into our body. And those toxins are causing specifically the kind of problems that we are seeing in the autistic children. They are interfering with mitochondrial effect. They are turning on and turning off genes. They are interfering with thyroid hormones, with estrogen and testosterone hormones.

Dr. Schwartz: And they persist in the body a long time.

18:49 Food Pesticides are our Major Toxin Source

Dr. Freedenfeld: Some of them persist. Some of them don’t. So the plastics are typically in and out. Some of them are persistent and will last for generations. The pesticides, for example, that is in food not grown organically. If you stop eating non-organic food, within 5 days, your urine is clear of insecticides and pesticides. It doesn’t mean your body’s clear, but your input is clear. So we always think about insecticides and pesticides coming from the spraying of the farms, even spraying of our lawns and spraying of our houses. But it has been shown that the major source in our bodies of pesticides is from our food. That is profound. If we can just make a decision at the grocery store to buy organic food.

Dr. Schwartz: That is important information. Really important. And I assume patients respond. And you’re seeing…

Dr. Freedenfeld: Well, it’s difficult to identify exactly what piece of the puzzle brought about the benefit, because we don’t do one thing at a time. Even in my best effort to be scientific and try one thing at a time, surely with supplements we will do one thing at a time. But when we are cleaning up the environment, I am going to be asking people to switch to organic food, to clean up their household products, to look at all of these aspects all that the same time.

Dr. Schwartz: So initially, do you do much testing or you just start with cleaning things up as much as possible.

Dr. Freedenfeld: Are we talking about autistic children?

Dr. Schwartz: Yeah.

20:29 Dr. Freedenfeld’s Approach

Dr. Freedenfeld: My approach with autism is to do very little with testing in the beginning. And generally, no invasive testing. I think that there is so much that needs to be done to get somebody on the right road with education, with getting their history, finding out their likely sources of problems are. Making environmental changes. Making dietary changes. Beginning some very fundamental but a broad base.of.supplements. I like to think of it as like laying a foundation upon which we will put pillars and build the second and third floor.

Dr. Schwartz: So what are your go-to foundation supplements?

 

 

21:13 Foundational Supplements

Dr. Freedenfeld: In the foundation we are generally going to look for a good quality multivitamin and additional methylfolate or folinic acid, magnesium, P5P form of B-6, a good fish oil, a zinc product and these are all added one at a time, watching what happens. I also like to use DMG (dimethylglycine) in that first visit, because used in a step-wise fashion as I have instructed people, will often bring about a dramatic improvement in brain function, in speech, and it gives parents a really quick feedback, like my child has got healing.

Dr. Schwartz: What kind of milligram dose do you go up to with your DMG?

Dr. Freedenfeld: So, I use a high concentration DMG that is 5 milligrams per ml, so 25 milligrams per teaspoon. We start with one ml and every 3 days, we will increase another ml, up to as much as 15 ml, 3 tablespoons a day, about 45-hundred milligrams. Single dose. It’s good tasting, very easy to get in. The instruction is that as you increase observe for improvement. This is the only thing you’re going to change at this time. Just observe for improvement. If 4 ml is better than 3 ml, go to 5. If 5 is better than 4, go to 6. If 7 is no better than 6 and 8 is no better than 6, than go back to 6. That’s your dose.

Dr. Schwartz: Gosh, so real individualized medicine. How much time do you suggest between adding supplements?

Dr. Freedenfeld: Really, as a 2 or 3 days, but also, if you’re not sure yet. A lot of kids, their functional behavior varies from day to day anyway. And other things happen. Aunt May came with the cat. There was a balloon outside the window that may have caused a..If you need to take longer, take longer. Be clear.

Dr. Schwartz: And when is your follow up after initial visit?

Dr. Freedenfeld: It takes about 6 weeks to get the initial stuff done.

23:30 Initial Patient Testing

Dr. Schwartz: And then you’ll start testing and that? The second visit?

Dr. Freedenfeld: Well, I will start testing with the first visit, but these are all non-invasive tests. So we’ll get a couple urine samples, a hair sample, a stool sample, so that we’ve got some more information as we go forward.

Dr. Scwartz: Okay. And when does chelation come into the picture. How do you test for…?

Dr. Freedenfeld: Well, not everybody needs chelation. So as we go through, at each visit we will try and identify what is most likely to help next. What’s the next door to pass through? And some of that is going to depend on what happened last time, the information about what supplements made you better, what made you worse, what had no difference, is all information that gets fed into the puzzle.

Dr. Schwartz: Into your bio computer?

Dr. Freedenfeld: Into my brain. What aspects the parents feel is most important to address next. So if sleep is most important, we are going to address sleep. If stimming is most important, we are going to address that. So we try to be selective there. But, then we’ll look at the simple lab tests that we have and help them make some decisions. We are going to go forward step by step and choose what we’ll do next.

Dr. Schwartz:   When you are evaluating a child, when might you do what we call the challenge test and when do you become more suspicious of a heavy metal toxic load?

24:56 Urine Porphyrin Test

Dr. Freedenfeld: Well you might see sometimes from the early hair testing show lots of heavy metals. Or you may be suspicious if we do a urine porphyrin test, that there is some element of toxicity there or an organic acid test that tells us there is a difficulty in dealing with toxic burden. That makes you a little more suspicious.

Dr. Schwartz: And could you clarify the difference for hair test for evaluation versus urine challenge where you get something to bind to metals. And the porphyrin test people might not know about how that’s a biochemical measure.

Dr. Freedenfeld: So, the urine porphyrin, when it initially was brought to the Think Tank, it was hailed as this great test to identify lead toxicity, mercury toxicity. My immediate reaction was, “No way.” We have 87,000 chemicals out there and this is just giving you a view into one window of the Titanic. This is not giving you solid information and, indeed, it’s not. So when the urine porphyrin test says there is toxicity, this is a pattern that we see with mercury toxicity that may or may not correlate with an actual sampling. It is suggestive of some impairment in a toxic burden.

Dr. Schwartz: So what do you use for really assessing toxic heavy metal burden?

26:19 Hair Sample Testing

Dr. Freedenfeld: The hair sample. It’s a nice piece of information, but it really is dependent on what the hair follicle biochemistry is using with its nutrients. So the hair follicle is making a hair and it takes nutrients. But like any other part of our body, it may be selective. So it may or may not choose to take lead and put it in the hair. Depending on the individuality, it may be better at that. Mercury is even more complicated because most of our body burden of mercury comes from dental amalgams. The form of mercury that comes from our teeth, does not deposit in the hair. So you could be very burdened with mercury, but the hair will be completely benign. If you eat fish, and that is where your mercury is coming from, we’ll see it in the hair.

Dr. Schwartz: So the urine test is the next step?

27:16 Urine Testing for Toxins

Dr. Freedenfeld: A urine test enables us to look into the body burden. If we do a random urine. We pee in a cup. We look at the amounts of mercury, lead, arsenic, cadmium; we get an idea of what is presently floating through the bloodstream, being filtered by the kidney, coming out the urine. When you get exposed to toxins, whether it is heavy metals or others, it will spend a certain amount of time in our bloodstream and then you’ll either pee it out, pooped out, or get incorporated it into your body. That part that is incorporated into the body, you’re not going to measure by looking in the blood or by looking in the urine, or by looking in the hair, necessarily.

28:02 Using Chelators for Testing

Dr. Freedenfeld: We want to do something to provoke a release. To dig into there, put our shovel in the sand and see what’s in there. Chelators are substances that strongly bind to metals. They will bind in that form, carry it through the bloodstream and it will be deposited in the liver and it goes out in the stool or it will be filtered through the kidney and goes out in the urine. So it gives us a reflection of the body burden. If you put in a shovel of a known size, and you get out one marble, there are probably not a whole lot of marbles. If you get out 30 marbles, it’s a different suggestion.

Dr. Schwartz: Good analogy. I’ll use that with my patients. ‘cause what I find, I don’t know about you. But there is a subset of kids who are off the chart. Most kids are going to fall in that what everyone would be exposed to today in modern living, but there are those kids that just chshht all the way off the chart in the red zone. Do you find there’s that subset?

Dr. Freedenfeld: There is a very large subset and it depends on how you do your provocation testing.

Dr. Schwartz: What do you use for your provocation? This is how you do your initial assessment, right?

Dr. Freedenfeld: I prefer to use an intravenous challenge to be able to understand what I’m going to be dealing with. I have tried oral DMSA for many years, even in somebody who I knew clinically was severely mercury toxic, just from the history, just from the situation and been very disappointed in the urine results from a properly done DMSA oral challenge.

Dr. Schwartz: Is that like a 6 hour collection?

Dr. Freedenfeld: It would be a 6 hour collection or a 12 hour collection with a dose of 25 to 30 milligrams per kilogram single dose before they go to bed and using overnight collection, would be the best way to do it. Then going back to those same people and retesting them with DMPS intravenously and see, Whoo, just a ton of mercury.

Dr. Schwartz: Okay, so you have. What practical results that you’ve seen?

Dr. Freedenfeld: DMPS is great at pulling mercury. It gives you good information there. But it is terrible at pulling lead, arsenic, cadmium, aluminum, and most of the other metals. But EDTA, the substance that has long been used for cardiovascular medicine is great at pulling those other substances and terrible at pulling mercury. So we will often do a combination. But I also recommend that people do glutathione infusions first. I want to be clear. We don’t jump into IV treatments early on in our treatments. We do everything else that we’ve taught people in the DAN! conferences and now at the MAPS conferences.

31:08 Glutathione before Chelation

Dr. Freedenfeld: But when it gets to the point where we are thinking that we are going to have to be taking the next step, we are going to look at something intravenously; I want to do glutathione first. Glutathione is a detoxifying substance. It is so commonly deficient in the children that we treat because it is dependent on proper methylation and proper sulfation. Both pathways that are interfered with in chemical toxicity. Because if that glutathione is low and kids respond incredibly well. So I will do a series of glutathione infusions starting with a low dose, building upward, again, “How did it work last time?” “What was the response?” and based on that, we’ll keep the same dose or go up in dose.

Dr. Schwartz: And what is your dosage range?

Dr. Freedenfeld: We usually start it around 600. Sometimes, we’ll start at 200.

Dr. Schwartz: For a child above a certain weight or..?

Dr. Freedenfeld: For a child, whether it is a 2 year old, 3 year old. Generally, the amount of glutathione that people will tolerate is pretty wide. Some are very sensitive to it in that they get really hyper and it’s just too much and we have to back down. There is nothing long lasting about that. Just a temporary…

32:23 Rare Reactions to Glutathione

Dr. Schwartz: Is that the worst adverse effect you’ve seen?

Dr. Freedenfeld: Pretty much. Rarely, we’ve seen people with allergic reactions to the mold source of the glutathione.

Dr. Schwartz: Oh, is that its source?

Dr. Freedenfeld: It’s made from, I’m blanking. It might be aspergillus. So they may react to aspergillus fragments. But that’s been rare. Nothing serious about it. Just an itchy throat kind of thing.

Dr. Schwartz: And one thing I think parents and other would want to hear about other forms of glutathione. What is most effective? What is the difference between the oral, the transdermal, the suppository.

33:11 Glutathione Efficacy in Different Delivery Methods

Dr. Freedenfeld: Far and away intravenous is the most effective. If you give transdermal glutathione, it is only really going to be effective in the skin. I believe that the benefit is from detoxing in that way. I am not aware of any studies that have shown an increase in blood glutathione levels after a transdermal. Suppository is fairly effective. The liposomal forms of glutathione. Oral glutathione will get absorbed into the first layer of cells in the intestines and have a nice effect there, but it is not going to get into your body. Liposomal form, liposome is a fat molecule wrapped around it so it is able to go through the intestinal cells and get into the lymphatics, into the bloodstream and get into your body that way. So that can have a benefit. The inhaled forms as a nebulizer is tremendously effect for pulmonary disease. I have the privilege of taking care for a woman who was scheduled for a lung transplant. I treated her with nebulized glutathione, amongst other things, and she is now off the transplant list and doing well.

Dr. Schwartz: What was her underlying problem?

Dr. Freedenfeld: She had severe interstitial pulmonary fibrosis and COPD. And the other form is a nasal glutathione that I helped to develop. Because the inhale glutathione goes to the lung, it is going to be taken up there and not get into the body very well. So we figured in the nose, we have the cribriform plate, the thin layer of cells at the top of the nose that is just a couple layers away from the brain. So in a slow nebulized form while the child is sleeping, because glutathione smells very bad of rotten eggs. So while the child is sleeping we just put these little prongs. They breathe it in during the night. It seems like we get good levels of glutathione that way. Enough that my patients who travel long distances for intravenous can do longer periods of time between intravenous needs by doing the nebulizer.

Dr. Schwartz: So this would be compounded?

Dr. Freedenfeld: It’s compounded.

Dr. Schwartz: What dosage? Is it a simple spray or how many times a day?

Dr. Freedenfeld: We’ll dose 200 milligrams is about all you can concentrate in there. Then once or twice a day. If you do it a second time, they would have to be awake and that would be pretty hard for the kids. For the adults, they could do.

36:03 Skin Testing for Toxins

Dr. Schwartz: And it’s okay. Well, that’s good to know. Is there a point where you might try and, I know there are some labs now that will offer glutens, pesticides, herbicides,

Dr. Freedenfeld: For testing? Not really. It’s a nice test, but the population studies have been very clear that we are all severely laden with these chemicals. We all have PCBs, Bisphenol A, phthalates, pesticides, flame retardant, jet fuel propellants. We have this all in our bodies. Every one of us. To test, doesn’t tell me anything. Because of the genetic component, it doesn’t so much matter how much you are exposed to as much as how much you can tolerate. How much you can dispose of.

Dr. Schwartz: Your individual system.

37:01 Assessing Exposure vs Ability to Detox

Dr. Freedenfeld: The studies that looked at exposure are not necessarily going to give us good information. There are studies that show gee the closer you live to farm fields that are sprayed with pesticides, the higher level you have been exposed to, the more likelihood that you will develop autism or ADD. But a lot of other studies have been very confusing and they don’t show that. But, to me, that’s not surprising because genetically we’re all different.

Dr. Schwartz: Yeah, I would like to think that, get your thoughts too, but more awareness, understanding of this environment. The studies that have just come out in the past year about air pollution about proximity to power plants, those are all older studies, I think.

Dr. Freedenfeld: Power plants, street car pollution.

Dr. Schwartz: So, do you feel there is more awareness on that environment question?

Dr. Freedenfeld: I think there is more awareness on the part of those people who are making themselves aware. Unfortunately, there is the choir and there is the rest. So the more we get the word out, and I think that this is one, hopefully, good forum to spread the word.

Dr. Schwartz: Yes. Yes. The reason we’re doing this. We really appreciate your time. I don’t know if you have any closing thoughts…

Dr. Schwartz: What is our best way to eliminate and avoid the endocrine disruptors, the plasticizers, the pollutants, the herbicides, the fungicides that are so far in the background, how do we…? Chelate and get rid of them.

38:26 Dr. Freedenfeld’s Web Site Education Gold Mine

Dr. Freedenfeld: Well, you may remember when I first gave the talks on preparing for the next baby; it was really depressing. I was personally depressed, about learning about what we’re doing. Presenting that information was very difficult to hear. It was just all “That’s bad.” “This is bad.” And over time, I realized that what we really need to know is how to avoid it and what else we can do. So I’ve spent a great deal of time in putting together information that is freely available on my website on alternatives. Where to find the pollutants. What can we do instead of plastics? What can we do instead of the normal building materials? What kind of carpeting is safe to use? What kind of cosmetics? There is just a huge array that is available in the educational section under environment.

Dr. Schwartz: Let me emphasis, and this will be on our website on the talks information, but Stocktonfp.com is Stu’s website. I referred many many patients to it because it has the most complete list I’ve seen of the clean sources, of the options. From bug repellant, to cleaners, to household insect control.

39:56 How Can We Detox?

Dr. Freedenfeld:   And then the other side of it when you’re exposed. Well, certainly the first order of environmental medicine is to stop the exposure. Then, how do we detox. So doing the things that we’ve learned about, methylation, sulfation are important, increasing glutathione production in our own body as well as, taking it in various ways. Saunas can be helpful. Infrared saunas.

Dr. Schwartz: That’s gotten a lot of documentation, as I’ve seen through the years.

Dr. Freedenfeld: Hyperbaric oxygen can help build antioxidative defenses and help blood flow. A number of nutrients will help to build glutathione, for example, like broccoli sprouts and pycnogenol, vitamin C, alpha lipoic acid, N-acetylcysteine, etcetera. There are just so many things that we can do nutritionally to get our bodies healthier so it is able to do what it naturally does. It gets rid of toxins.

40:59 Farewell

Dr. Schwartz: Okay, well thanks for that wonderful informative. I think it will be helpful to a lot of people. It was a real pleasure to be with you, Stu. And I appreciate you taking the time out of your very busy schedule.

Dr. Freedenfeld: Thank you for taking the time out to do this wonderful research and get this together for all those people to see.

Dr. Schwartz: Thanks. Pleasure.[/text_block]

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